Our new Clear+ tissue clearing method is the one system that delipidates samples without having change in morphology and with minimum effect on structural integrity.
Megatome can be a vibrating microtome built to portion a broad array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits substantial-throughput tissue sectioning with uniform floor profile, as well as minimum tissue injury and data reduction.
Antibodies may perhaps take months to diffuse by means of just a few millimeters of tissue, using a steep labeling gradient from surface area to core.
Megatome is made for accuracy: the blade vibrates at a higher frequency and larger amplitude range than other microtomes, and features a unique deflection control system.
SE makes use of a rotational electric field to disperse highly electromobile molecules (which include antibodies or surfactant micelles) all over a porous sample devoid of detrimental electrically charged structures within the tissue. This allows two-4 day clearing of intact organs,
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eFLASH is often a fast tissue labeling system that permits for uniform whole-organ staining in twenty rounds of labeling.
Entirely delipidate entire mouse brains or comparably sized samples in just one working day with SmartBatch+, or in a single week with our passive clearing package.
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Leverage the Clear+ tissue clearing approach, along with eFLASH and patented stochastic electrotransport technologies, to swiftly crystal clear and label full organs. Important highlights and options contain:
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